“Śrīla Viśvanātha Cakravartī Ṭhākura has stated, kalau dravya-deśa-kriyādi-janitaṁ durvāram apāvitryam api nāśaṅkanīyam iti bhāvaḥ. In this age the world is so polluted by sinful life that it is very difficult to become free from all of the symptoms of Kali-yuga. Still, one who is faithfully serving in the missionary work of Caitanya Mahāprabhu need not fear occasional, unavoidable symptoms of Kali-yuga. The followers of Caitanya Mahāprabhu strictly follow the four regulative principles of no illicit sex, no intoxication, no meat-eating and no gambling. They try to always chant Hare Kṛṣṇa and engage in the service of the Lord. However, it may happen that by accident an occasional symptom of Kali-yuga such as envy, anger, lust, greed, etc., may momentarily appear in the life of a devotee. But if such a devotee is actually surrendered at the lotus feet of Caitanya Mahāprabhu, by His mercy such an unwanted symptom, or anartha, will quickly disappear. Therefore, a sincere follower of the Lord should never be discouraged in the execution of his prescribed duty but should be confident that he will be protected by Caitanya Mahāprabhu.
It is also mentioned in this verse, śiva-viriñci-nutam. Lord Śiva and Lord Brahmā are undoubtedly the two most powerful personalities within this universe. Still, they meticulously worship the lotus feet of Caitanya Mahāprabhu. Why? Śaraṇyam. Even Lord Śiva and Lord Brahmā are not safe without the shelter of the lotus feet of the Lord.”
A.C. Bhaktivedanta Swami Prabhupada (2014 edition), “Srimad Bhagavatam”, Eleventh Canto, Chapter 05 – Text 33.